The reference site for Norethindrone

Norethisterone (NET), also known as norethindrone, is a medication that is used in combination with estrogen or alone in hormonal contraceptives, hormone replacement therapy, and in the treatment of gynecological disorders.

WHAT IS Norethindrone?

Norethindrone is a synthetic oral progestin (female hormone).

It is used for contraception or to treat such conditions as secondary amenorrhea, abnormal uterine bleeding, and endometriosis. As an oral contraceptive, norethindrone is available as either a single agent or in combination with an estrogen.

In medical terms, progestins diffuse freely into target cells and bind to the progesterone receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH surge.

 

Brand Name(s): Aygestin; Camila; Errin; Nor-QD;Ortho Micronor
CAS nº: 68-22-4
(nor ETH in drone)

 

Product Info

The sections below will provide you with more specific information and guidelines related to norethindrone and its correct use. Please read them carefully.

FDA Information

The FDA approved norethindrone in 1957 for menstrual disorders and the treatment of infertility. Following this, the contraceptive application was approved by the FDA in 1960.

Interestingly enough, Australia was the first country to approve the contraceptive pill after the USA. Japan was the last industrialized country to do so in 1999.

Since the synthesis of norethindrone in 1951, seven closely related steroids have been developed by five pharmaceutical companies and these are the active ingredients of the hundreds of birth control pills sold all over the world. To this day, norethindrone is consumed by millions of women.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Norethindrone is a synthetic oral progestin (female hormone).

It is used for contraception or to treat such conditions as secondary amenorrhea, abnormal uterine bleeding, and endometriosis. As an oral contraceptive, norethindrone is available as either a single agent or in combination with an estrogen.

Mechanism of action:
Progestins diffuse freely into target cells and bind to the progesterone receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH surge.

Other uses for this medicine

This medication has not been approved for any alternative uses other than those mentioned in the product information section.

Dosage and using this medicine

Norethindrone comes as a tablet to be taken orally.

The dose schedule for norethindrone may be different for birth control than for treating other conditions. To best treat your condition, norethindrone should be used exactly as your doctor has prescribed it for you. Do not use more of the medication than recommended, and do not take it for longer than your doctor has prescribed.

Take the medication at the same time each dose day. Taking a pill late or missing a pill can increase your chances of having breakthrough bleeding or getting pregnant.

For birth control, start a new pack of pills the day after your last pack is finished. There is no break between packs.

If you vomit soon after taking norethindrone, use a backup method of birth control (such as a condom and/or spermicide) for 48 hours.

You may have some light bleeding or spotting between periods. Continue taking norethindrone even if this occurs.

If your menstrual period is late you may be pregnant. If it has been more than 45 days since the start of your last period, call your doctor or use a home pregnancy test.

You will need to have yearly physical exams and Pap smears while you are using norethindrone. Examine your breasts at home every month to check for lumps. It is important that you not miss any scheduled visits to your doctor.

After you stop using norethindrone, you may start bleeding within a few days.

What special precautions should I follow?

BEFORE TAKING NORETHINDRONE:

Norethindrone is in the FDA pregnancy category X. This means that using the medication while you are pregnant can cause birth defects in the baby. Do not take norethindrone if you are pregnant. Stop taking the medication and tell your doctor if you become pregnant, and if you plan to become pregnant after you stop taking norethindrone, ask your doctor how long you should wait before trying to get pregnant.

Tell your doctor if you have high blood pressure, angina, heart disease, a bleeding disorder such as hemophilia, diabetes, high cholesterol, migraines, a history of depression or mental illness, asthma, seizures or epilepsy. If you have any of the conditions listed above, you may not be able to use norethindrone or you may require a dosage adjustment or special monitoring during treatment.

Additionally, you should not take this medicine if you have a history of stroke or blood clots, liver disease, cancer of the breast of ovary, unusual vaginal bleeding that a doctor has not diagnosed, or complications from a recent miscarriage or abortion. Taking this medicine may be dangerous if you have any of the conditions listed above.

Please inform your doctor if you are taking any of the following medicines: rifampin (Rifadin®), phenytoin (Dilantin®), carbamazepine (Tegretol®), or a barbiturate such as amobarbital (Amytal®), butabarbital (Butisol®),mephobarbital (Mebaral®), secobarbital (Seconal®), or phenobarbital (Luminal®, Solfoton®). If you are using any of these drugs, this medicine may not work as well and you may get pregnant. You may need to use a second form of birth control if you are taking any of the medicines listed above.

There may be other drugs not listed that can affect norethindrone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors.

This medication can pass into breast milk and may harm a nursing baby. Do not use this medicine without telling your doctor if you are breast-feeding.

Taking this medicine can cause you to have unusual results to certain medical tests. Tell any doctor who treats you that you are using norethindrone.

Women who use hormone medication should not smoke. Smoking will increase your risk of having a serious side effect from norethindrone, such as heart attack, stroke, or a blood clot.

This medicine does not protect you from sexually transmitted diseases, including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. Then take the next dose at your regularly scheduled time. Do not take extra medicine to make up the missed dose.

If you were more than 3 hours late in taking your dose, use a backup method of birth control (such as a condom and/ or spermicide). Keep using the backup method for at least 48 hours to ensure protection from pregnancy.

If you are not sure what to do about a missed dose, keep taking norethindrone and use a backup method of birth control until you can talk to your doctor.

What side effects can this medication cause?

Stop using norethindrone and call your doctor at once if you have any of these serious side effects:

an allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue, or face, or hives)
abnormal vaginal bleeding
late or missed menstrual period
a partial or complete loss of vision, blurred vision, double vision, or a sudden onset of bulging eyes
sudden and severe headache, pain behind your eyes, dizziness or fainting
speech problems
vomiting or jaundice (yellowing of the skin or eyes)
sudden or severe pain in your lower stomach

Other, less serious side effects may be more likely to occur. Continue to take norethindrone and talk to your doctor if you experience:

nausea
swollen or tender breasts
sleep problems (insomnia)
depression, mood swings
acne, freckles, or darkened skin areas
increased hair growth
weight gain or loss
changes in your menstrual cycle or vaginal discharge

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Please remember to throw away any medication that is outdated or no longer needed. Should you have any questions, talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

An overdose of norethindrone is not likely to cause serious overdose symptoms. However, in the case of a suspected overdose, call your local poison control center on 1-800-222-1222. If the victim has collapsed or is not breathing, then please call the local emergency services immediately on 911.

Symptoms of a norethindrone overdose have not been reported.

Product Images

PICTURES OF NORETHINDRONE PILLS

Below you will find images and specific information on the principal types of norethindrone that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: CAMILA®
Strength(s): 0.35 MG
Imprint: CAMILA
Manufacturer: BARR LABS.

Name: ERRIN®
Strength(s): 0.35 MG
Imprint: ERRIN
Manufacturer: BARR LABS.

Name: ORTHO MICRONOR®
Strength(s): 1.35 MG
Imprint: ORTHO MICRONOR
Manufacturer: ORTHO PHARM.

Contact us